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Osteomyelitis can happen if a bacterial or fungal infection enters the bone tissue from the bloodstream, due to injury or surgery. Most often the bacteria are staphylococcus, but in sickle-cell children, both salmonella and staphylococcus are implicated. The bacteria are haematogenously disseminated and deposited in the trabecular bone or marrow, usually in the metaphysis of the proximal tibia or distal femur. Oteomyelitis manifests in patients with sickle cell anaemia when there is infections thorough some bacteria and could affect the bones with attendants effect in the activity of bone marrow which will affect the solid phase of blood and the quality of lives of the sickle cell anaemia patients. Preventive measures such personal hygiene should be adopted to avoid the danger such inflammation could cause in the patients.

Urinary tract infections are regarded as one of the most infection diseases caused by bacteria, especially in females, as it’s estimated that 50% of all women get at list a urinary tract infection during their life time. In community settings, urinary tract infections mainly affect women that are active sexually, whereas among the middle hospitable, they are the people of old age and the carriers, who are mostly affected. Allium sativum has for many years been known and used as one of the best active herbal plants for management of various illnesses caused by bacteria. Garlic exhibits broad spectrum antimicrobial activity against both Gram positive and Gram-negative bacteria.The inhibitory effect of fresh garlic extract against gram negative multidrug resistant bacteria was the same as compared to the inhibitory effects attained from the drug-susceptible strains of Escherichia. Coli.